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Mouse embryos（胚胎） have been cultured（培养） on the International Space Station (ISS), marking a significant step in understanding reproduction in space. Led by Teruhiko Wakayama from the University of Yamanashi in Japan, this experiment studied the possible safety of human pregnancy（怀孕） during long space journeys, such as a trip to Mars that lasts more than six months. Wakayama emphasized the importance of this research, saying, "We are conducting research to ensure we will be able to safely have children if that time comes."

The experiment began on Earth, where early two-cell stage embryos from pregnant mice were taken out, frozen, and sent to the ISS on a SpaceX rocket. Astronauts on the ISS then warmed up and cultured the embryos for four days using devices specially designed for this task. Afterward, the embryos were kept and returned to Earth. The four-day growth period was chosen as embryos can only survive for this length outside a uterus, according to Wakayama.

Upon their return, the embryos were examined to check the impact of space's unique conditions, such as higher radiation（辐射） levels and microgravity（微重力). The results were promising; the embryos showed no DNA damage from radiation and showed normal structural development, including the crucial change into two cell groups necessary for forming the fetus and placenta. Wakayama found these results significant, as it was previously believed that microgravity might prevent the embryo's ability to separate into these separate cell types.

While these findings are promising, further research is needed to fully understand space reproduction. Wakayama referred to a previous study involving pregnant rats in space, which resulted in the birth of typical-weight rats, suggesting normal development. The team now aims to further study the health of embryos exposed to space conditions and plans to test whether mouse embryos sent to the ISS can develop into healthy young after returning to Earth. 

A company run by Google, called DeepMind, has found a way to predict diseases in people using artificial intelligence(AI). This is the name given to a computer system that can "think" for itself and perform tasks that usually require human intelligence such as problem-solving and decision-making.

Google DeepMind is an AI company that works with scientists, engineers and researchers to solve difficult challenges using technology. They say their aim is to advance science and benefit humanity, and their research includes finding ways to use technology to identify and treat diseases. 

DeepMind's new software, AlphaMissense, works by looking at DNA. This is a chemical found in all animals and plants that carries information about every living thing's appearance and characteristics.

DNA is made up of four chemical "bases". These are known as A, T, G and C. The order that these bases are arranged in is very important, because it provides the instructions for how a life-form will develop. If the bases aren't in the right order, this can create something called missense mutations（突变）. These are mostly harmless, but in some cases they lead to diseases, including sickle cell disease, which affects people's blood, and cystic fibrosis, which affects lungs and digestive(消化的） systems.

There are millions of possible missense mutations. Scientists had only classified (归类) 0.1% of these as either benign or potentially (潜在的) disease-causing. However, the AlphaMissense software has now classified an impressive 89% of them. The DeepMind team have shared their findings in the hope that it will help doctors and scientists spot disease-causing mutations and start treating people sooner. 

Genomics England (GE), a company that works with the NHS to analyse people's DNA, has already tested the software. Dr Ellen Thomas, from GE, said it will help scientists "make sense of genetic data", so that patients can get better treatments.

The city of San Francisco, California, is known as a city that loves food. There are many award-winning restaurants. San Francisco is also a city that loves dogs. So, dog owner and chef Rahmi Massarweh decided to combine his two loves into one. He has opened the first and only restaurant for dogs. The restaurant is called Dogue. The name is like the word "vogue", which means "fashion". It opened in September in the city's popular Mission District.

Individual dishes cost around $30. Or, for $75 each, dogs can dine on a multi- course "bone appetite" meal. Some people are expressing their opinions about the costly menu. But Massarweh has received a lot of support from his customers. They are thankful to have a place to treat their furry friends. Recently, Dogue held three dog birthday parties at the same time.

Gledy Espinoza is the owner of Mason, an 11-year-old miniature dachshund (迷你腊肠犬). Mason enjoyed some mushroom soup with pieces of chicken. "I wanted to celebrate for him. He is so special to me. He's my four-legged child and this is the perfect place to have a really nice celebration. We're foodies (吃货). I guess he is too, now," Espinoza said.

Massarweh uses costly ingredients (材料) to prepare his food. Everything he makes could be eaten safely by humans, but we probably would not like it. The dog dishes may taste flavorless to us. Dogue's goal is to spread the idea of feeding dogs fresh, healthy, and natural food. Some research shows that natural food may be better for a dog's stomach than the dog food that you can buy in a store.

DiscoverCars.com have ranked the best destinations in Europe for an autumn getaway. The top four destinations for a European Autumn getaway were:

⒈Barcelona, Spain

Barcelona takes first place in DiscoverCars. com's ranking of the best destinations in Europe for an autumn getaway. With the highest number of cheap restaurants (1,793) and low-cost hotels (534), there are certainly plenty to choose from when visiting the Catalonian city.

The average cost of a week long hotel stay in Barcelona is priced at £981 while plane tickets from Heathrow cost £141 on average during Autumn.

⒉Lisbon, Portugal 

Next, Lisbon ranked in second place – also moving up one position from last year's results. Lisbon is home to 455 low-cost hotels and has the highest average temperature from September to November out of all cities examined (18° Celsius).

The journey from London Heathrow to Lisbon Humberto Delgado Airport costs £148 on average while vehicles are available for hire for £159.

⒊Berlin, Germany

Moving on, in third place is the German capital, Berlin. The city improved from 2022's results where the location ranked in fourth place. Berlin offers visitors a choice of 1,422 cheap eateries and 360 low-cost hotels throughout the city.

Additionally, the average cost of a week-long hotel stay totals £827 while the average amount of daylight throughout Autumn is 10.7 hours.

⒋Budapest, Hungary

In fourth place is Budapest—the top-rated destination 12 months ago. Budapest has an average of 56mm of rainfall during the Autumn months, the second lowest out of all cities investigated.

Budapest is also a very affordable（价格合理的） city, with the average price of a flight from Heathrow costing £160 while a week-long hotel stay is priced at £600 on average.

From the first day he entered my classroom, Henry existed in his own world, shutting out his classmates and me. My attempts at building a friendly relationship with him were met with complete indifference. I could see that his classmates fared no better. Henry was strictly a loner who seemed to have no desire or need to break his silence.

Shortly after the Thanksgiving holiday, we received word of the annual Christmas collection of money for the less fortunate people in our school district.

"Christmas is a season of giving." I told my students, "There are a few students in the school who might not have a happy holiday season. To make donations to our Christmas collection, you can buy food, clothing and toys for these people in need. We will start the collection tomorrow."

When I called for the donations the next day, I discovered that almost everyone had forgotten except Henry. The boy dug deep into his pants pockets when he walked slowly to my desk. Carefully, he dropped two coins into the small container.

"I don't need milk for lunch." He mumbled（含糊地说话）. For a moment, just a moment, he smiled. Then he turned and walked back to his desk.

That night, after school, I took our few donations to the school principal（校长）. I couldn't help sharing the story that had taken place in my class.

"I may be wrong, but I believe Henry might be getting ready to become a part of the world around him," I told the principal.

"Yes," he nodded. "And we might do well to have him share a bit of his world with us. I just received a list of the poor families in our school who need help the most through the Christmas collection. Here, take a look at it."

As I gazed down to read, I discovered Henry and his family were the top names on the list. Seeing this, I decided to do something for him.

注意：1.续写词数应为150左右｡2.请按如下格式在答题卡的相应位置作答｡

Paragraph 1:

On that Sunday, I paid a visit to Henry's family. 

Paragraph 2:

The next day, I had a special class for Henry. 

注意：1.写作词数应为80左右；2.请按如下格式在相应位置作答。

Dear my fellow students,

I am Li Hua, Minister of Sports Department of Youth League General Branch 

……

Student Union.

The Yungang Grottoes in Datong, Shanxi Province,  UNESCO World Heritage Site, have 45major caves and more than 59,000 Buddha statues, with a grotto complex about 1 km long from east to west.

(current), a giant 3D printing reproduction of Cave No.3 at the Yungang Grottoes is display at the Yungang Grottoes Art Museum in Qingdao, east China's Shandong Province. This is the first time in the world that 3D printing technology (use) to reproduce such a large-scale cultural relic.

The identical reproduction strictly matches the (appear) and scale of the original. The copy of the cave measures 17.9 meters tall by 13.6 meters wide, while the main Buddha stands at 9.93 meters tall.

During the replication process, 3D technicians first (collect) some 10, 000 images of the cave and the Buddha to build up a digital model,  was then divided into 842 parts to be printed with multiple 3D printers. The final installation（安装） and coloring stages took the team three months (complete).

The reproduction not only allows people to get much (close) to the precious heritage items without damaging the original objects, but also helps to enhance the research, documentation, digitalization and preservation of the (relic) themselves.

Jeffrey is a millionaire. Years ago, after returning from abroad, he 1 his small company. Speaking of success, Jeffrey often tells about his extra expensive "school" fee, which he always 2 his success to.

After getting a Ph. D. degree, Jeffrey decided to return to the homeland, starting a company. Before leaving, he bought a Rolex watch with the 3 earned through years of work. At the airport he had to accept the 4 customs check. The watch on his wrist was also demanded to be taken down for 5 . Jeffrey knew that carrying the specific goods out had to pay the tax, and he worried about paying it for his watch. So when he was checked, he told a lie that his watch was a 6 fake（假货）. When he was 7 of his "smarts", immediately, in the presence of Jeffrey, the officers 8 the watch, which cost nearly 100,000, into pieces on hearing Jeffrey's words. Jeffrey was 9 . Before he understood why, he was taken to the office to be examined 10 . The officers looked over everything carefully in the box, and 11 him that he must accept the check and if found carrying fake goods, he would be 12 according to law! Suddenly, his face turned red, and he had nothing in mind after 13 the plane for long.

The additional high "school" fee that he had ever paid made him realize the value of 14 , which he would remember as the 15 of his success forever.

Within weeks of chatbots' launch, ChatGPT triggered a new global race in artificial intelligence. The chatbots are part of a fresh wave of so-called generative AI—sophisticated systems that produce content from texts to images. However, one key lesson concerning AI chatbots is to lower our expectations.

Don't use chatbots for factual answers

Google and Wikipedia aren't perfect, but they're good enough for reliable factual information most of the time. That average might be correct or surprisingly wrong. And if the chatbot doesn't know the answer, it might invent a reasonable-sounding answer.

When you are planning a birthday party, you can type into ChatGPT for help with the invitation. AI had sucked up a bunch of children's party invitations from the internet. You can have a glimpse at what all those party-throwing parents had done before.

Do know what chatbots are best at

Chatbots can be amazing at explaining complicated topics like cryptocurrencyn（加密电子货币） as though you're 5 years old. To understand this strength, it helps to know that the software has been fed files from Reddit, including a forum called "Explain Like I'm Five." That makes ChatGPT good at personalized recipe planning. Again, you should treat ChatGPT less as a reliable cookbook and more as a meal-planning brainstorming partner.

Don't get frustrated and give up

 The five minutes of travel planning with ChatGPT could have popped up some ideas for you to research further.

A. Don't ask a chatbot once and stop.

B. Do use chatbots to help you brainstorm.

C. Similarly, there are loads of recipes on the internet.

D. ChatGPT can suggest loads of ideas that you can run with.

E. ChatGPT is less like a Magic Ball and more like a brainstorming partner.

F. While chatbots are far from perfect, they are worth an investment of your time.

G. AI chatbots give you the average response from information the software has absorbed.

After almost an entire year of not going shopping and vacationing, you find the numbers reflected by your bank account meet your heart's desire.

Now the most important question comes, what to do with the earnings? Should you fulfill dreams of the present, invest in preserving the future or perhaps keep saving it for a rainy day?

Our elders always try to teach us the value of money and its moral weakness. One may be on a winning streak（连续成功） now, but it will not always be so. One will have days when there will be no sunshine but only rain and their luck will hide behind those thick grey clouds. Save for those rainy days, they say. Do not spend too much, live within a budget, refrain from credit no matter how small and save for the future.

Since the very first time we earn our own money from a summer job, the lessons start. In fact, the pocket money that we receive when we are children begins the process of learning how to best manage one's money.

People often think like this-one day when I have enough money, I will travel around the world. Then, once we do earn enough money, tomorrow's plans start shadowing our present ones. However, is it wise to keep living for that future? Will we still enjoy or even be able to backpack in our 50s? How will we ever enjoy our present if we are constantly living for the future?

Good questions, aren't they? I say travel but don't let yourself run dry, treat yourself to some luxuries but also keep enough for your necessities, and enjoy your present but with a plan for the foreseeable future. Life is for the living. So live it sensibly.